Adaptive reorientation of endothelial collectives in response to strain
نویسندگان
چکیده
منابع مشابه
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.
Cyclic mechanical strain produced by pulsatile blood flow regulates the orientation of endothelial cells lining blood vessels and influences critical processes such as angiogenesis. Mechanical stimulation of stretch-activated calcium channels is known to mediate this reorientation response; however, the molecular basis remains unknown. Here, we show that cyclically stretching capillary endothel...
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ژورنال
عنوان ژورنال: Integrative Biology
سال: 2018
ISSN: 1757-9694,1757-9708
DOI: 10.1039/c8ib00092a